Takeaway
The degeneration of retinal ganglion cell dendrites followed by a reduction in mitochondrial volume and distribution in human glaucomatous eyes may be an early sign of glaucoma.
Why this matters
Glaucoma is the leading cause of irreversible blindness and detecting early signs of retinal damage remains a challenge. The results of this study may lead to a clinically detectable target for early retinal neuronal damage which could translate to a viable therapy for human glaucoma.