Neurofilament light chain levels influence ability of physical activity to slow cognitive decline rate in older adults

Takeaway

  • Moderate or high levels of physical activity can slow cognitive decline in older adults, but the magnitude of effect varies according to serum neurofilament light chain levels.

Why this matters

  • The relationship between serum neurofilament light chain levels and physical activity with the rate of cognitive decline in older adults is unclear.
  • The findings of this unique study suggest that people with higher serum neurofilament light chain levels may need to engage in greater levels of physical activity to slow cognitive decline.