Predicting epilepsy risk after the first seizure

Takeaway

  • Quantifying paroxysmal slow wave events (PSWEs) using electroencephalography (EEG) in patients presenting with their first seizure was able to distinguish patients with epilepsy from those who would not experience a repeat seizure.

Why this matters

  • Epileptic seizures account for 2–3% of all emergency department presentations. However, the suspected event is typically not observed by healthcare professionals and hence reaching a likely diagnosis (e.g., isolated event, first seizure due to epilepsy, or seizure mimic) is difficult.

  • EEG is a feasible tool for assessing patients who experience seizure. A possible biomarker of epilepsy measurable via EEG are PSWEs. It is possible that interictal EEG with an automated algorithm for measuring PSWEs could be a useful and reliable indicator of epilepsy.