Takeaway
A data-driven approach identified clinical amyotrophic lateral sclerosis (ALS) subgroups, which correspond with the subgroups defined by an existing clinical classification system.
Why this matters
ALS is a clinically heterogeneous disorder that is characterized by progressive muscular atrophy.
Early classification of patients to subgroups can further help understand the disease’s heterogeneity, assist with disease management, and lead to effective treatment therapies.